Why is skin antisepsis the most important part of the blood culture collection procedure?

{Can just answer the questions- Thanks for the help!}
Blood Culture Case Study
D.M. is a 53-year-old man with a history of Guillian-Barre syndrome and septicemia of antibiotic-resistant bacteria in the bloodstream. Once admitted to the hospital, the patient complained of shortness of breath and tachycardia. He had a temperature of 102°F. Two sets of blood cultures were ordered 6 hours apart.
What do blood cultures help a physician to determine?
What is meant by a blood culture set? Why are two sets of blood cultures ordered?
How is a blood culture obtained? Explain the procedure and the reasons for each step.
Why is skin antisepsis the most important part of the blood culture collection procedure?
Why is the mention of the 102°F temperature included in the scenario?

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